Natural Product Synthesis & Chemical Biology

Alumni
Dr. Benke Hong
Dr. Yang Zhang
Mengjiao Zhang
Jinze Chai
Xucai Wang
Megnyang Wang
Chuning Guo
Zhiyuan Liang
Yaoyao Xu
Weiqiang Guan
RA 2019.7-10

Education Background

07. 2016 - 06. 2019

Research Assistant in Chemical biology

Peking University, Beijing

Advisor: Professor Xiaoguang Lei

09. 2011 - 06. 2016

Ph.D. in Applied Chemistry,Tianjin University and NIBS (National Institute of Biological Sciences, Beijing)

Advisor: Professor Xiaoguang Lei

09. 2007 - 06. 2011

B.S. in Pharmaceutical Engineering, Liaoning University

Advisor: Professor Lifeng Xu

Award

China National Scholarship of Graduate Students, 2015

Outstanding Student Scholarship, National Institute of Biological Sciences (NIBS), 2014

Outstanding Undergraduate Thesis Award, Liaoning University, 2011

Publication

1. Benke Hong, Dagny Grzech, Lorenzo Caputi, Prashant Sonawane, Carlos E. Rodríguez López, Mohamed Omar Kamileen, Néstor J. Hernández Lozada, Veit Grabe & Sarah E. O’Connor, Nature 2022, 607, 617–622.

2. Yunpeng Ji†, Benke Hong†(†co-first author), Ivan Franzoni, Mengyang Wang, Weiqiang Guan, Hongli Jia, Houhua Li, Angew. Chem. Int. Ed. 2022, DOI:10.1002/anie.202116136.

3. Benke Hong, Tuoping Luo, Xiaoguang Lei, ACS Cent. Sci. 2020, 6, 622-635.

4. Jin Wang†, Benke Hong (†co-first author), Dachao Hu, Yuichiro Kadonaga, Ruyao Tang, Xiaoguang Lei, J. Am. Chem. Soc. 2020, 142, 2238-2243.

5. Benke Hong, Weilong Liu, Jin Wang (†co-first author), Jinbao Wu, Yuichiro Kadonaga, Pei-Jun Cai, Hong-Xiang Lou, Zhi-Xiang Yu, Houhua Li*, Xiaoguang Lei, Chem 2019, 5, 1671-1681.

6. Benke Hong, Dachao Hu, Jinbao Wu, Jing Zhang, Houhua li, Yingming Pan, Xiaoguang Lei, Chem. Asian J. 2017, 12, 1557-1567.

7. Benke Hong†, Chao Li†
(†co-first author), Zhen Wang, Jie Chen, Houhua Li*, Xiaoguang Lei, J. Am. Chem. Soc. 2015, 137, 11946−11949.

8. Benke Hong†, Houhua Li† (†co-first author), Jinbao Wu, Jing Zhang, Xiaoguang Lei, Angew. Chem. Int. Ed. 2015, 54, 1011−1015.

Dr. Benke Hong
Dr. Yang Zhang

Education Background

07.2019-09.2022: Post-Doctoral Fellow, School of Pharmaceutical Sciences, Peking University

Advisor: Prof. Houhua Li

09.2015-07.2019: Ph.D.
Major: Organic Chemistry, Technical university Dortmund, Dortmund, Germany
09.2012-07.2015: Master of Science
Major: Organic Chemistry, Sichuan University, Chengdu, China
Advisor: Prof. Xiaoqi Yu
09.2009-06.2011: Double Degree
Major: Project Management, Three Gorges University, Yichang, China
09.2008-06.2012: Bachelor of Science
Major: Chemicobiology, Three Gorges University, Yichang, China

Award

Excellent Graduate Three Gorges University Scholarship (First, Second and Third year) Outstanding Student Cadres Chinese Government Scholarship

Publication

1. Long-Hua Zhou, Na Wang, Guan-Nan Chen, Qi Yang, Sheng-Yong Yang, Wei Zhang, Yang Zhang, Xiao-Qi Yu. (2014) Lipase-catalyzed highly diastereoselective direct vinylogous Michael addition reaction of α,α-dicyanoolefins to nitroalkenes. J. Mol. Catal. B: Enzym. 2014, 109, 170-177.

2. Yang Zhang, Na Wang, Zong-Bo Xie, Long-Hua Zhou, Xiao-Qi Yu. (2013) Ionic liquid as a recyclable and efficient medium for lipase-catalyzed asymmetric cross aldol reaction. J. Mol. Catal. B: Enzym. 2014, 110, 100-110.

3. Yang Zhang†, Yunpeng Ji†(†co-first author), Ivan Franzoni, Chuning Guo, Hongli Jia, Benke Hong, Houhua Li. Angew. Chem. Int. Ed. 2021, 60, 14869-14874.

PD 2019.7-2022.9
RA 2010.7-10

M/F: Female

Date of Birth: July, 1993 Nationality: P. R. China
Address: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Road 38, Beijing 100191, China  
Education
09.2017-07.2020: Master of Science.
Major: Pharmaceutical chemistry, Peking Union Medical College.
09.2012-07.2016: Bachelor of Science.
Major: Pharmaceutics, Tianjin University.

Mengjiao Zhang
UG 2018-

M/F: Male

Date of Birth: March, 2001

Nationality: P. R. China

Address: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Road 38, Beijing 100191, China

Jinze Chai
RA 2019.7-2021.1

M/F: Male
Date of Birth: March, 1991

Nationality: P. R. China
Address: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Road 38, Beijing 100191, China

Phone: +86 18801379172

E-mail: wangxucai@bjmu.edu.cn

Education
07.2019- present: Research Assistant.

School of Pharmaceutical Sciences, Peking University.(with Pro. Houhua Li)
09.2016-06.2019: Master of Science

Major: Organic Chemistry,Department of Chemistry & Materials Science. Northwest University.

Advisor: Prof. Zhenghui Guan

08.2011-07.2015: Bachelor of Science

Major: Chemistry, College of Chemistry and Chemical Engineering, Hexi University.

Pubilcation
1. Ming Chen, Xucai Wang, Pengfei Yang, Xun Kou, Zhi‐Hui Ren, Zheng‐Hui Guan. Angew. Chem. Int. Ed. 2020, 59, 121992.

2. Ming Chen†, Xucai Wang† (co-first author), Zhi-Hui Ren, Zheng-Hui Guan. CCS Chem. 2021, 3, 69–77

Xucai Wang
MS 2020.9-2022.07
Mengyang Wang

M/F: Male

Date of Birth: August, 1997

Nationality:  P. R. China

Address: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Road 38, Beijing 100191, China

Phone: +86 13766468141

E-mail: 1610307128@pku.edu.cn

Education

09.2020-07.2022: Master of Science

Major: Chemical Biology, School of Pharmaceutical Sciences, Peking University.

Advisor: Prof. Houhua Li

09.2016-07.2020: Undergraduate

School of Pharmaceutial Sciences, Peking University

Publication

1. Yunpeng Ji†, Benke Hong†(†co-first author), Ivan Franzoni, Mengyang Wang, Weiqiang Guan, Hongli Jia, Houhua Li, Angew. Chem. Int. Ed. 2022, 61, e202116136.
Chuning Guo

M/F: Female

Date of Birth: August, 1998

Nationality: P. R. China

Address: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Road 38, Beijing 100191, China

Phone: +86 18801380085

E-mail: m18801380085@163.com

Education

09.2020-07.2022: Master of Science

Major: Chemical Biology, School of Pharmaceutical Sciences, Peking University.

Advisor: Prof. Houhua Li

09.2016-07.2020: Undergraduate

School of Pharmaceutial Sciences, Peking University

Publication

1. Yang Zhang†, Yunpeng Ji†(†co-first author), Ivan Franzoni, Chuning Guo, Hongli Jia, Benke Hong, Houhua Li*
Angew. Chem. Int. Ed. 2021, 60, 14869-14874 (Selected as Hot Paper)
MS 2020.9-2022.07
UG 2017-
M/F: Male
Date of Birth: September, 1998

Nationality: P. R. China
Address: School of Pharmaceutical Sciences, Peking University, Xue Yuan Road 38, Beijing 100191, China
Phone: +86 18501190233
E-mail: liangzy17@bjmu.edu.cn

Zhiyuan Liang
Yaoyao Xu
M.S 2020.9-2023.7

M/F:Male

Date of birth: June, 1997

Nationality: P. R. China

Address: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Road 38, Being 100191, China.

Phone: +86 18868110681

E-mail: 3160104472@zju.edu.cn


Education

09.2020-07.2023: Master of Science

Major: Chemical Biology, School of Pharmaceutical Sciences, Peking University.

Advisor: Prof. Houhua Li

09.2016-07.2020: Bachelor of Science

Major: Pharmaceutics, Zhejiang University.


Weiqiang Guan

M.S 2021-2024

M/F: Male

Date of Birth:  November, 1998
Nationality: P. R. China
Address: School of Pharmaceutical Sciences, Peking University, Xue Yuan Road 38, Beijing 100191, China
Phone: +86 13304594365
E-mail: gwq9474@pku.edu.cn

Education

09.2021-07.2024: Master of Science

Major: Chemical Biology, School of Pharmaceutical Sciences, Peking University.

Advisor: Prof. Houhua Li

09.2017-07.2021: Undergraduate

School of Pharmaceutial Sciences, Peking University

Address: 38 Xueyuan Rd, Haidian Distrcit, Beijing, 100191, China
Email:Lihouhua@pku.edu.cn
Tel:+86-10-82805512